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Literature summary extracted from

  • Que, B.G.; Davie, E.W.
    Characterization of a cDNA coding for human factor XII (Hageman Factor) (1986), Biochemistry, 25, 1525-1528.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.21.38
-
Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.38 Homo sapiens
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.4.21.38 proteolytic modification when the contact phase of coagulation or fibrinolysis is initiated, factor XII is converted to factor XIIa by cleavage of a single internal Arg-Val peptide bond. This reaction occurs in the presence of kallikrein, an ionic surface, and high molecular weight kininogen Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining